an article by Dimy Fluyau (Emory University, Atlanta, USA), Paroma Mitra (NYU, New York, USA) and Kervens Lorthe (Miami Regional University, Miami Springs, USA) published in frontiers in Psychiatry (15 October 2019)
Background
Among individuals experiencing amphetamine psychosis, it may be difficult to rule out schizophrenia.
The use of antipsychotics for the treatment of amphetamine psychosis is sparse due to possible side effects.
Some arguments disfavor their use, stating that the psychotic episode is self-limited.
Without treatment, some individuals may not fully recover from the psychosis and may develop full-blown psychosis, emotional, and cognitive disturbance.
This review aims to investigate the clinical benefits and risks of antipsychotics for the treatment of amphetamine psychosis.
Methods
Electronic search on trials on antipsychotic drugs for amphetamine psychosis from their inception to November 2018 was conducted in PubMed, Scopus, Google Scholar, EBSCOhost, ProQuest, Cochrane Review Database, Medline Ovid, and EMBASE following the Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines.
The Cochrane risk-of-bias tool assessed the risk of bias, the methodological quality of individual trials was assessed by the Oxford Quality Scoring System, and the quality of evidence for recommendations was judged by the Grading of Recommendations, Assessment, Development, and Evaluations (GRADE).
The results were synthesized qualitatively and quantitatively.
Results
The investigation of six randomized controlled trials of 314 participants showed that aripiprazole, haloperidol, quetiapine, olanzapine, and risperidone were able to reduce or control the psychotic episode (positive and negative symptoms) induced by amphetamine use with no adverse event.
Although the side-effect profile of these agents varied, no drug was clinically superior to others.
Conclusions
This review suggests that antipsychotics seem to be efficacious for amphetamine psychosis on both positive and negative symptoms.
Practitioners need to tailor their use based on risks for side effects individually.
Full text (PDF 14pp)
Please note:
This source produces information for practitioners but sometimes, as now, contains something which I think is of more general interest.
Showing posts with label psychosis. Show all posts
Showing posts with label psychosis. Show all posts
Thursday, 24 October 2019
Tuesday, 15 October 2019
Telling it like it is: opening up about my vulnerability
a post by May-May Meijer for the OUP blog
Image by Daniel Reche from Pixabay
It was quite a shock for me when the independent psychiatrist asked me during my forced stay in the mental hospital what I thought of my diagnosis “schizophrenia”. It was the first time I heard my diagnosis. For the rest of our conversation the diagnosis “schizophrenia” echoed in my head. I associated “schizophrenia” with: being an outcast and violence. It was as if I was told that I was inferior and no longer part of society. Because of my illness, my husband wanted a divorce from me, I saw my child less, I quit my job at the university, and the side effects of the medicines I fell into a depression. I felt lonely and useless.
Hiding my mental illness
In the beginning I had difficulties talking about my illness. I published writings about my experiences using a pseudonym. When I still worked at the university, I didn’t dare tell my colleagues that I had suffered from a psychosis. After I quit my job, I wanted to find a new job desperately. I was afraid that an employer wouldn’t hire me if I discussed my illness. That is why I didn’t mention it on job applications. I did mention it twice, for job applications in the mental health sector. For one position, they offered me a voluntary job instead of the paid job they advertised for in the ad.
Continue reading
Image by Daniel Reche from Pixabay
It was quite a shock for me when the independent psychiatrist asked me during my forced stay in the mental hospital what I thought of my diagnosis “schizophrenia”. It was the first time I heard my diagnosis. For the rest of our conversation the diagnosis “schizophrenia” echoed in my head. I associated “schizophrenia” with: being an outcast and violence. It was as if I was told that I was inferior and no longer part of society. Because of my illness, my husband wanted a divorce from me, I saw my child less, I quit my job at the university, and the side effects of the medicines I fell into a depression. I felt lonely and useless.
Hiding my mental illness
In the beginning I had difficulties talking about my illness. I published writings about my experiences using a pseudonym. When I still worked at the university, I didn’t dare tell my colleagues that I had suffered from a psychosis. After I quit my job, I wanted to find a new job desperately. I was afraid that an employer wouldn’t hire me if I discussed my illness. That is why I didn’t mention it on job applications. I did mention it twice, for job applications in the mental health sector. For one position, they offered me a voluntary job instead of the paid job they advertised for in the ad.
Continue reading
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